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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHX
All Species:
29.09
Human Site:
S65
Identified Species:
45.71
UniProt:
O00330
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00330
NP_001128496.1
501
54122
S65
K
I
L
M
P
S
L
S
P
T
M
E
E
G
N
Chimpanzee
Pan troglodytes
XP_001149489
501
54051
S65
K
I
L
M
P
S
L
S
P
T
M
E
E
G
N
Rhesus Macaque
Macaca mulatta
XP_001109997
446
48686
Q50
W
R
W
F
H
S
T
Q
W
L
R
G
D
P
I
Dog
Lupus familis
XP_533153
501
54075
S65
K
I
L
M
P
S
L
S
P
T
M
E
E
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKZ9
501
53981
S65
K
V
L
M
P
S
L
S
P
T
M
E
Q
G
N
Rat
Rattus norvegicus
P08461
632
67147
R74
Q
L
L
G
S
P
S
R
R
S
Y
S
L
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026358
502
53201
G65
L
S
P
T
M
E
E
G
N
I
V
K
W
L
K
Frog
Xenopus laevis
NP_001087423
478
50485
K65
G
N
I
V
K
W
L
K
K
E
G
E
S
V
S
Zebra Danio
Brachydanio rerio
NP_956854
490
51982
S71
K
V
Q
M
P
A
L
S
P
T
M
E
E
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624025
598
64649
S172
N
I
G
M
P
A
L
S
P
T
M
T
S
G
T
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
S86
R
V
A
L
P
A
L
S
P
T
M
E
L
G
T
Sea Urchin
Strong. purpuratus
XP_001177721
482
51019
T65
I
M
P
A
L
S
P
T
M
T
E
G
T
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WQF7
637
68844
S94
V
L
A
M
P
A
L
S
P
T
M
S
H
G
N
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
I68
Q
L
S
P
G
E
V
I
A
E
I
E
T
D
K
Red Bread Mold
Neurospora crassa
P20285
458
48601
I62
Q
K
K
P
G
D
K
I
E
P
G
E
V
L
V
Conservation
Percent
Protein Identity:
100
99.5
87
90.2
N.A.
85.2
34.4
N.A.
N.A.
72.1
58.8
58
N.A.
N.A.
36.4
37.2
47.3
Protein Similarity:
100
99.8
87.6
93.2
N.A.
91.4
49.6
N.A.
N.A.
82
73.4
73
N.A.
N.A.
51.6
56.7
63
P-Site Identity:
100
100
6.6
100
N.A.
86.6
6.6
N.A.
N.A.
0
13.3
80
N.A.
N.A.
60
53.3
13.3
P-Site Similarity:
100
100
13.3
100
N.A.
100
26.6
N.A.
N.A.
13.3
33.3
93.3
N.A.
N.A.
66.6
80
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.9
32.7
34.7
Protein Similarity:
N.A.
N.A.
N.A.
48.9
51.9
51.1
P-Site Identity:
N.A.
N.A.
N.A.
60
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
7
0
27
0
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
0
7
7
0
% D
% Glu:
0
0
0
0
0
14
7
0
7
14
7
60
27
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
7
7
14
0
0
7
0
0
14
14
0
54
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
7
27
7
0
0
0
0
14
0
7
7
0
0
7
7
% I
% Lys:
34
7
7
0
7
0
7
7
7
0
0
7
0
0
14
% K
% Leu:
7
20
34
7
7
0
60
0
0
7
0
0
14
14
0
% L
% Met:
0
7
0
47
7
0
0
0
7
0
54
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
0
0
7
0
0
0
0
0
40
% N
% Pro:
0
0
14
14
54
7
7
0
54
7
0
0
0
14
7
% P
% Gln:
20
0
7
0
0
0
0
7
0
0
0
0
7
0
0
% Q
% Arg:
7
7
0
0
0
0
0
7
7
0
7
0
0
0
0
% R
% Ser:
0
7
7
0
7
40
7
54
0
7
0
14
14
0
7
% S
% Thr:
0
0
0
7
0
0
7
7
0
60
0
7
14
0
14
% T
% Val:
7
20
0
7
0
0
7
0
0
0
7
0
7
7
14
% V
% Trp:
7
0
7
0
0
7
0
0
7
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _